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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease polycystic ovary syndrome
Comorbidity C0003128|anovulation
Sentences 30
PubMedID- 22128296 Clomifene citrate or low-dose fsh for the first-line treatment of infertile women with anovulation associated with polycystic ovary syndrome: a prospective randomized multinational study.
PubMedID- 23183180 Hyperandrogenism seems to be a central factor in pcos, leading to anovulation and insulin resistance.
PubMedID- 23321213 Loss of lh-induced down-regulation of anti-mullerian hormone receptor expression may contribute to anovulation in women with polycystic ovary syndrome.
PubMedID- 20074021 pcos may be associated with chronic anovulation and endometrial hyperplasia.
PubMedID- 19409546 Objective: to explore an optimal laser dose of transvaginal ultrasound-guided ovarian interstitial laser coagulation in management of anovulation in patients with polycystic ovary syndrome (pcos).
PubMedID- 24520334 Hyperinsulinemia, a condition in which there is an excess level of insulin circulating in the blood, in women with pcos leads to anovulation, impairs folliculogenesis, and affects follicular development [40].
PubMedID- 26048913 Summary answer: involvement of intrinsic gc dysregulation in oligo-anovulation associated with polycystic ovary syndrome (pcos) is likely because among women with pcos, those with oligo-amenorrhea have higher per-follicle amh production than those who ovulate normally, irrespective of their androgen and/or metabolic status.
PubMedID- 23081959 Background: polycystic ovary syndrome (pcos) is associated with chronic oligo-anovulation and high circulating sex hormone levels.
PubMedID- 22554176 Second-line surgical interventions for anovulation associated with pcos include laparoscopic ovarian diathermy, which is as effective as medical induction of ovulation with gonadotropins, with a much reduced risk of multiple pregnancy.
PubMedID- 24273971 Objective: to observe the efficacy of danzhi xiaoyao pill (dxp) in anovulation infertility patients with polycystic ovary syndrome (pcos) of pathogenic fire derived from stagnation of gan-qi (pfdsg) complicated insulin resistance (ir).
PubMedID- 25343339 Their female offspring (n = 12) were studied during their second breeding season when the pcos-like phenotype, with anovulation, is fully manifest.
PubMedID- 23988170 Multiple regression model revealed that the presence of anovulation in pcos women was strongly associated with bmi, waist, fsh and age.
PubMedID- 26568493 Data suggest that anovulation in pcos is not the consequence of increased androgen ovarian secretion but rather of a severe derangement of early follicle development.
PubMedID- 22563801 anovulation was due to polycystic ovary syndrome in 12 (16.22%) cases and due to other causes in six patients (8.11%).
PubMedID- 25009725 A moderate male factor could be detected, an investigation of the women revealed the diagnosis of anovulation due to pcos (polycystic ovary syndrome).
PubMedID- 20205744 A woman with a suspicion of chronic anovulation most probably due to polycystic ovary (pco) syndrome, as there is a long history of irregular cycles and clinical presentation with hirsutism, her serum levels of testosterone hormone, sex hormone binding globulin (shbg), dihydroepiandrostenedione (dhea), dihydroepiandrostenedione-sulfate (dheas) and prolactin should be evaluated to prove the provisional diagnosis and to detect the source of excess androgens.
PubMedID- 21849061 Aside from early animal data [1-4], this was mostly due to the hyperandrogenism observed in many classical pcos patients, associated with anovulation and inferior oocyte quality in ivf [5].
PubMedID- 22723725 These risks, along with the anovulation associated with pcos, are often exacerbated by the excess body weight that often accompanies pcos.
PubMedID- 23926541 Results: the highest pregnancy rates were obtained in cases whose infertility duration was shorter (p < 0.05), body mass index (bmi) was >/=25 (p < 0.05), fsh < 9 iu/l (p < 0.05), anovulation due to polycystic ovary syndrome (p < 0.05), donor sperm was used due to azoospermia (p < 0.01), three iui cycles (p < 0.01), at least two follicles were recruited through controlled ovarian hyperstimulation (p < 0.01), and where higher total doses of fsh were administered as necessary (p < 0.05).
PubMedID- 25653680 Although clomiphene citrate (cc) is the first-line of treatment for chronic anovulation among women with pcos, failure to ovulate after receiving 150 mg/day is common and occurs in approximately 15% to 40% of women [7].
PubMedID- 25036703 Her past history was relevant only for anovulation due to polycystic ovarian syndrome (pcos), though her preprocedure body mass index was normal at 21 kg/m2.
PubMedID- 24842895 Participants/materials, setting, methods: a group of 20 overweight/obese pcos women with anovulation, hyperandrogenism and polycystic ovaries were subjected to a combined diet and exercise program for 3 months.
PubMedID- 25594860 The mother of our first patient (4) had actually reported a history of pcos with oligomenorrhea and anovulation, but at the time had not provided serum or urine for more detailed androgen analysis.
PubMedID- 21521255 All probands had pcos, defined by symptoms of anovulation and/or hyperandrogenism with polycystic ovaries on ultrasound.
PubMedID- 20362969 Aberrant follicle development and anovulation in polycystic ovary syndrome.
PubMedID- 20096985 Results: a significantly lower serum active/total ghrelin ratio was noted in the more severe form of pcos with hyperandrogenemia, chronic anovulation and polycystic ovarian morphology.
PubMedID- 22091305 Its prevalence was 33.9% in the subjects according to nih criteria and 13.1% in the pcos women with only anovulation and pco.
PubMedID- 26507336 Polycystic ovarian syndrome (pcos) induces anovulation in women of reproductive age, and is one of the pathological factors involved in the failure of in vitro fertilization (ivf).
PubMedID- 25050308 anovulation due to pcos is the most common cause of infertility in women (engman et al., 2005 ▶).
PubMedID- 21737073 Result(s): serum amh concentration was significantly raised in women having world health organization group 2 anovulation, either with or without pcos, and was significantly decreased to very low levels in pof; the diagnostic accuracy in both conditions was excellent, with areas under the receiver operating characteristic curve (auc) of 0.913 and 0.977, respectively.

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